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Cows' Milk Allergy

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Cows’ Milk Allergy Weaning Guide

The weaning guide contains recipes developed with leading dietitians from across the UK to help your patients' carers prepare milk-free recipes. The weaning guide can help give them confidence, that as their child grows, family meals can be adapted to make them suitable for CMA.

Cows’ Milk Allergy Symptom Diary

The symptom diary is for a carer of an infant suffering from signs and symptoms that could be linked to Cow's Milk Allergy (CMA) or other food allergies. Help your patients carer prepare for their next health visit, learn about common symptoms, which will help inform you to make a correct diagnosis.

A complex cows’ milk allergy patient using an amino acid formula

THE DIETARY MANAGEMENT OF A COMPLEX COWS’ MILK ALLERGY PATIENT USING ALFAMINO® A 2 month old baby was referred for Nasogastric feeding following an episode of bronchiolitis. The baby had a past medical history of atopic eczema and was previously managed by the GP and Allergy & Dermatology team. Patient’s background, medical history, physical diagnosis The patient was born full term in August 2014. Pre-October 2014, there was one admission to hospital fo...

A practical approach to managing a CMA infant with an extensively hydrolysed formula

A practical approach to managing a CMA infant with Althera™ Cows’ Milk Allergy (CMA) can occur in 1.8% - 7.5% of infants in the first year of life.1 The allergy is defined as an adverse reaction to the proteins in milk with most children growing out of their allergy by the time they reach one year. The treatment consists of the exclusion of cows’ milk from the infant’s diet. There...

Evaluation of hypoallergenicity of a new, amino-acid based formula

Cows’ milk allergy (CMA) is one of the major food allergies during infancy and childhood. Hypoallergenic formulas can be necessary for managing infants and children with severe CMA. According to the American Academy of Pediatrics (AAP), a formula is “hypoallergenic” if it does not provoke allergenic activity in 90% of infants or children with confirmed CMA with 95% confid...

Managing CMA with an Amino Acid Formula (AAF)

" MANAGING COWS’ MILK PROTEIN ALLERGY WITH ALFAMINO® Overview of cows’ milk protein allergy in infants Cows’ milk protein allergy (CMPA) is one of the most common food allergies in infants.1 Symptoms of CMPA include :  Gastrointestinal (32-60% cases) Skin (5-90%) Anaphylaxis (0.8-9%) Respiratory Many of these symptoms overlap. CMPA can be classified into two groups: IgE mediated or non-IgE mediated (delayed hypersensitiv..."

Managing faltering growth with an Amino Acid Formula (AAF)

" THE USE OF AMINO ACID FORMULA IN THE DIETARY MANAGEMENT OF SEVERE INFANT COWS’ MILK ALLERGY Approximately 2-7.5% of infants have symptoms of CMA1 whilst symptoms suggestive of Cows’ Milk Allergy (CMA) may be encountered in up to 15% of infants,  emphasising the importance of controlled elimination/milk challenge procedures2. The diagnosis and treatment pathways for cases of CMA are well documented and several guidelines exist to support the healthcare professional in..."

Safety and Efficacy of a new extensively hydrolyzed formula for infants with Cows’ Milk protein allergy

Cows’ milk protein allergy (CMPA) is the leading cause of allergy in infants. Previous studies assessing milk formulas with extensively hydrolyzed proteins have reported issues such as reactivity to residual allergens, bitter taste, and the impracticability of adding lactose.

The importance of having a choice of eHF and AAF milks in the management of CMA

During the last decade, the prevalence of allergic diseases in infants and children has increased significantly either through better awareness of the symptoms or through generally more children being affected.1-3 Therefore, it is no surprise that the numbers of children presenting to clinics in district general hospitals has also increased.4-5 Diagnosis of true milk allergy is key...

The prevalence of lactose intolerance in children with non-IgE-mediated gastrointestinal cows’ milk protein allergy (CMA)

Differentiating milk allergy (IgE and non-IgE from lactose intolerance: understanding the underlying mechanisms and presentations.

What do we know about lactose?

There is much confusion between the diagnostic terms ‘lactose intolerance’ and ‘cows’ milk allergy’, which are often used interchangeably, resulting in the potentially incorrect clinical management of these two distinct conditions.

Hypoallergenicity of a whey-based, extensively hydrolysed infant formula prepared with non porcine enzymes

To characterize the peptide profile of a whey-based, extensively hydrolysed formula (eHF) prepared with a non porcine enzyme blend, and to assess whether it meets the hypoallergenicity criteria of the Ame...

Controversies on Special Products for Managing Cow’s Milk Protein Allergy in Infants: Safety and Suitability

The aim of the symposium was to share learnings from the recently established European Academy of Allergy and Clinical Immunology (EAACI) Task Force on special products for cow’s milk protein allergy (CMPA), with the intention of providing an overview on controversies regarding extensively hydrolysed formulas (eHFs), their utility, and the validity of the definition ‘special products ...

Towards Optimised Management of Cow’s Milk Protein Allergy

This symposium took place during the 2018 meeting of the European Academy of Allergy and Clinical Immunology (EAACI). Focussing on the fundamental issues of suboptimal management of patients with cow’s milk protein allergy (CMPA), the speakers discussed key themes for optimising management.

Growth in Infants with Cows’ Milk Allergy Fed an Amino Acid-Based Formula

To assess if an amino acid-based formula supports normal growth in infants with cow's milk protein allergy (CMPA).

The Cows’ Milk Allergy-Related Symptoms Score (CoMiSS™): A Useful Tool in the Clinical Setting - Results from an Observational Study

The CoMiSS score was developed as an easy-to-use awareness tool for primary health care providers to increase the awareness of the most common symptoms of cow's milk protein allergy (CMPA) and the evolution of symptoms during a therapeutic intervention. The purpose of the study was to evaluate the score in infants with symptoms indicative of CMPA and to evaluate...

Hypoallergenicity of A Whey-Based, Extensively Hydrolysed Formula Containing Two Structurally Identical Human Milk Oligosaccharides

To determine whether an extensively hydrolyzed formula (EHF) supplemented with two human milk oligosaccharides (HMO) was tolerated by infants with cow’s milk protein allergy (CMPA). Methods: A whey-based EHF (Test formula) containing 2′fucosyl-lactose (2′FL) and lacto-N-neotetraose (LNnT) was assessed for clinical hypoallergenicity and safety. The Control formula was...

Human Milk Oligosaccharides: New Ways to Shape the Gut Microbiome in Cows’ Milk Protein Allergy

Prof O’Mahony began by discussing how the human gut is colonised by a wide diversity of microbes. He went on to review the evidence for how they exhibit highly evolved synergistic relationships to provide essential biological functions to the host and how the gut microbiome is influenced by many factors in early life. Prof Renz proceeded to describe the importance of establishing a s..

Twins with cows’ milk allergy step down from AAF to EHF

16 weeks old, female twins were identified on EMIS search at a GP practise by an Oviva community dietitian for review. They were not already under the care of a dietitian and had both been started on Neocate LCP® for suspected cows’ milk allergy (CMA) at 6 weeks old by a paediatrician. The dietitian successfully switched both twins to SMA Alfamino and later stepped them down to SMA Althera.

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Other content you might be interested in
Cow’s Milk Allergy in Primary Care

This webinar, hosted by Dr. Helen Evans-Howells, focuses on recognising and managing cow’s milk protein allergy (CMPA) in primary care. It offers an overview of how to effectively work with patients who have CMPA in a community setting. Key learning points include the differences between allergies and intolerances, when to test for allergies and how to interpret results, and insights into the future of food allergies. The session concludes with an informative Q&A session.

SMA Althera and SMA Alfamino - Clinical Evidence Book

WHAT MAKES AN EFFECTIVE SPECIALIST CMA FORMULA? Very few eHFs and AAFs have been shown effective, both in terms of allergy and growth.6,7 At Nestlé Health Science, we set the highest standards for our CMA formulas, SMA® Althéra® and SMA® Alfamino®, ensuring both manufacturing excellence and robust clinical evidence to demonstrate: Proven hypoallergenicity  According to guidelines, the gold standard is for hypoallergenic formulas to be tolerated by at least 90% of infants with proven CMA (with 95% confidence interval) in a clinical trial.1,3,6  Growth and development  According to guidelines, the gold standard is for hypoallergenic formulas to demonstrate normal growth in a clinical trial, because whilst eHF and AAF nutritional profiles are governed by strict regulations,7,8 there are still significant compositional differences between brands.5 REFERENCES: 1. Luyt D et al. Clin Exp Allergy 2014; 44: 642–672. 2. Grimshaw K et al. Clin Transl Allergy 2016; 6: 1. 3. Koletzko S et al. JPGN 2012; 55(2): 221–229. 4. Muraro A et al. Allergy 2014; 69(5): 590–601. 5. Meyer R et al. EMJ Allergy and Immunol. 2017; 2(1): 46–51. 6. Chauveau, A. et al. Pediatr Allergy Immunol. 2016; 27(5): 541–543.   7. Commission Delegated regulation (EU) 2016/128. 8. Commission directive 1999/21/EC

Diagnosing and Managing Cows' Milk Allergy

The aim of this webinar is to aid primary care individuals in the diagnosis and management of cows' milk protein allergy. Evidence suggests that it can take an average of 10 weeks and 4 visits to a healthcare professional to get a diagnosis of cows' milk allergy (CMA).1

Could I recommend a carer adding anything to the formula to make it taste better?

Kate discusses how adding flavours isn’t recommended - she further discusses how formulas containing lactose can taste better and therefore may be tolerated better.

Are there any vitamins or minerals I should be prescribing?

Helen discusses the vitamins and minerals needed with both breastfed infants and formula fed infants both with or with cows’ milk allergy.

The dietary management of Cows' Milk Allergy in Primary Care

A webinar explaining the dietary management of Cows’ Milk Allergy in primary care. 

Cows’ Milk Allergy Weaning Guide

The weaning guide contains recipes developed with leading dietitians from across the UK to help your patients' carers prepare milk-free recipes. The weaning guide can help give them confidence, that as their child grows, family meals can be adapted to make them suitable for CMA.

Allergy tests to diagnose cows’ milk protein allergy

Professor Antonella Muraro, Paediatric Allergist, discusses the tests available to help support diagnosing CMA in infants. Filmed 2017.

Weaning with cows’ milk allergy: what does this mean in practice?

Rachel DeBoer, specialist paediatric allergy dietitian, discusses the challenges faced when weaning (complementary feeding) infants with CMA. Filmed in May 2017.

Practical tips for managing feeding aversions in the allergic child

Food allergies can have an impact on eating habits and food intake. This includes CMA where feeding difficulties has been described as a possible feature. Dr Polly James, paediatric clinical psychologist, discusses practical tips for managing feeding aversions in the allergic child. Filmed in May 2017

The Benefits of Human Milk Oligosaccharides (HMO) on Immunity

Human milk contains bioactive components that confer protection on the newborn. These include complex carbohydrates called Human Milk Oligosaccharides (HMO). Research is revealing the full extent of the beneficial properties of HMOs.

Lactose Intolerance: Common Misunderstandings

Lactose intolerance is one of the more common forms of food intolerance and is often confused with cows' milk allergy. This video explains the differences in both symptoms, diagnosis and treatment. It also explains the different types of lactose intolerance.