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Webinar - Fibre and Peptide Feeds: From historical avoidance to evidence-based inclusion

Webinar - Fibre and Peptide Feeds: From historical avoidance to evidence-based inclusion

Join us for an insightful session as we trace the evolution of enteral nutrition, moving from the historical avoidance of fibre and peptides to their role as evidence-based essentials. The speakers discuss the clinical shift in perspective and explore how new innovations may support patient outcomes through improved tolerance and absorption. the event is follow up with recorded live Q&A.To download the full trial - Acceptability and tolerance study of a high‑protein semi‑elemental feed containing PHGG fibre | N+ HubTo explore more about Peptamen HN PHGG , please visit Peptamen® HN PHGG | N+ Hub

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Acceptability and tolerance study of a high‑protein semi‑elemental feed containing PHGG fibre
Fibre
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Acceptability and tolerance study of a high‑protein semi‑elemental feed containing PHGG fibre

METHOD A prospective, singlearm multicentre study was carried out to assess GI tolerance and compliance to a new formula, Peptamen HN PHGG®. Participants were under the care of a Dietitian and recruited from two NHS settings. Participants were adults who were tube fed, receiving >60% of their estimated requirements enterally, experiencing GI discomfort (diarrhoea, constipation, excessive wind or nausea) and able to consent. RESULTS 21 participants (30–88 years), identified by Dietitians as meeting inclusion criteria, were consented and enrolled; 13 participants had completed the trial at the time of writing. Primary diagnoses included oesophageal cancer, GI tract surgery, pancreatitis, aspergilloma, EhlersDanlos, and myasthenia gravis. Four participants were fed into the stomach and nine into the jejunum. All patients began the trial due to diarrhoea. At baseline, 92% (n=12) had a type 6 or 7 stool; one patient had an ileostomy reporting diarrhoea. At the end of the study, 77% (n=10) reported a type 4 or 5 stool, with only 23% (n=3) still reporting type 6 or 7. Average stool frequency decreased from 2.9 to 2.3 per day. 77% (n=10) reported improved tolerance after starting the formula. 92% (n=12) tolerated the prescribed volume; 54% (n=7) tolerated a higher volume compared to their previous feed. CONCLUSIONS Tubefeed tolerance remains a challenge. Historically, Dietitians have needed to choose between a semielemental peptidebased feed or a fibre feed. This study shows Peptamen HN PHGG® was well tolerated by most participants, with reductions in undesirable GI symptoms, improvements in stool frequency and type, increased compliance, and high satisfaction levels.

Listen: Fibre Inclusion in Paediatric Enteral Feeding with Mikayla Profe-Fuchsloch

Information for Healthcare Professional Use Only In this episode of the Inside Medical Nutrition podcast, Dr. Linia Patel speaks with Mikayla Profe-Fuchsloch, a dietitian and assistant professor at the University of Coventry, about the impact of fibre inclusion in enteral nutrition for paediatric patients. Fibre, which is classified by solubility, viscosity, and fermentability, increases stool weight, improves bowel regularity, and can balance stool frequency in both diarrhoea and constipation cases. All these features make it a useful addition to enteral nutrition. It is not uncommon when managing paediatric patients with complex medical needs to have issues related with the gastrointestinal system.  There can be issues with gut dysmotility and symptoms such as gastroesophageal reflux, delayed gastric emptying, diarrhoea and constipation. In clinical practice, adding in a fibre supplement or choosing a fibre containing enteral feed can help to manage these issues. Current guidance from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition on how much fibre per day paediatric patients require recommends an increased fibre intake in children with neurodisabilities of 17-21g of fibre per day.1 This may be provided by the fibre from an enteral feed as well as the addition of a fibre supplement.  Fibre supplements that are partially hydrolysed, such as Partially Hydrolysed Guar Gum (PHGG), which can help to improve bowel motions1. PHGG has been shown to work as a prebiotic, supporting the growth of beneficial gut bacteria2,3,4. In addition, the combination of peptide-based feeds and fibre can help to improve tolerance and gastrointestinal symptoms.  Mikayla shares a case study where PHGG fibre supplementation significantly improved bowel motions and reduced medication reliance in a child with complex clinical conditions. She stresses the importance of a gradual introduction of fibre, monitoring tolerance through detailed symptom diaries, and involving parents in the decision-making process. She also points out the lack of standardised tools for fibre introduction, emphasising individualised approaches. Listen to the full podcast episode to learn more about fibre inclusion in enteral nutrition and the role it plays. 1.    Romano C, van Wynckel M, Hulst J, et al. J Pediatr Gastroenterol Nutr. 2017;65:242–264 2.    Ohashi Y, et al. Benef Microbes 2015;6(4):451-455.  3.    Yasukawa Z, et al. Nutrients 2019;11(9):2170.  4.    Reider SJ, et al. Nutrients 2020;12(5):1257.